赵霞,女,理学博士,教授,博士生导师。2002年9月至2006年7月在南开大学攻读学士学位。 2006年9月至2011年7月在北京大学攻读博士学位。2008年9月至2011年7月,在日本北海道大学亚洲联合研究生院攻读博士学位。2011年7月进入威尼斯wns885566工作至今。其间,2012年入选天津市131人才第三层次人选,2014年入选天津市用三年时间引进千名高层次人才项目,2015年入选天津市131人才第二层次人选,2016年获得教育部自然科学一等奖。2016年入选天津市中青年骨干培育计划,独立工作以来发表sci论文40余篇,授权发明专利7项。
电子邮箱:hxxyzhx@tjnu.edu.cn
教学工作:
本科生基础课程 <<有机化学2-1>>,<<有机化学2-2>>
科研工作:
1、 涉及硫/硒元素的小分子有机合成方法学研究
2、 植物抗逆性生长调节剂的开发及其机制研究
主要研究项目:
1、 国家自然科学基金 面上项目 通过自由基加成/环化策略合成含硫药物活性分子及相关活性分子的作用机制和作用靶点研究 2023.1-2026.12
2、国家自然科学基金 面上项目 磺酰肼作为硫化试剂构建碳-硫键的研究 2016.1-2019.12
3、国家自然科学基金 青年项目通过催化脱氢偶联实现芳香杂环直接烷基化的 2013.1-2015.12
4、天津市高等学校科技发展基金 青年项目 磺酰氯作为硫代试剂对黄酮类化合物的硫醚化反应研究 2018.9-2021.10
主要论著:
(1) p-Toluenesulphonicacid-promoted, I2-catalysed sulphenylation of pyrazolones with aryl sulphonyl hydrazides. Xia Zhao,* LipengZhang, Tianjiao Li, Guiyan Liu, HaomengWang and Kui Lu*, Chem. Commun. 2014, 50, 13121.
(2) Synthesisof 2-Aryl and 3-Aryl Benzo[b]furanThioethers Using Aryl Sulfonyl Hydrazides as Sulfenylation Reagents. Xia Zhao,* LipengZhang, Xiaoyu Lu, Tianjiao Li and Kui Lu* J. Org. Chem. 2015, 80, 2918.
(3) Transition-Metal-Free Direct Trifluoromethylthiolation and Trifluoromethylsulfoxidation of Electron-Rich Aromatics with CF3SO2Na in the Presence of PCl3 Xia Zhao, *Aoqi Wei, Bo Yang, Tianjiao Li, Quan Li, Di Qiu, and Kui Lu J. Org. Chem., 2017, 82 (17), 9175
(4) Transition-Metal Free Direct Difluoromethylthiolation of Electron-Rich Aromatics with Difluoromethanesulfonyl Chloride. Xia Zhao,* Aoqi Wei, Tianjiao Li, Zhiyang Su, Jun Chen and Kui Lu* Org. Chem. Front., 2017, 4(2), 232.
(5) Metal-free oxidative cross-coupling of diazirines witharylboronic acids. Guojiao Wu, Xia Zhao, *Wenzhi Ji, Yan Zhang and Jianbo Wang* Chem. Commun. 2016, 52, 1961 (Highlighted by Synfacts 2016, 12(3), 0294)
(6) Recent Developments in Copper-Catalyzed Reactionsof Diazo Compounds. Xia Zhao, * Yan Zhang and Jianbo Wang, * Chem.Commun. 2012, 48, 10162.
[8] Transition-Metal-Free Direct Trifluoromethylthiolation and Trifluoromethylsulfoxidation of Electron-Rich Aromatics with CF3SO2Na in the Presence of PCl3. Xia Zhao,* Aoqi Wei, Bo Yang, Tianjiao Li, Quan Li, Di Qiu, Kui Lu*, J. Org. Chem., 2017, 82, 9175.
[9] Transition-Metal Free Direct Difluoromethylthiolation of Electron-Rich Aromatics with Difluoromethanesulfonyl Chloride. Xia Zhao,* Aoqi Wei, Tianjiao Li, Zhiyang Su, Jun Chen, Kui Lu*, Org. Chem. Front., 2017, 4, 232.
[10] Visible-Light Photocatalytic Trifluoromethylthiolation of Aryldiazonium Salts: Conversion of Amino Group into Trifluoromethylthiol Group. Xia Zhao,* Xiancai Zheng, Miaomiao Tian, Yifan Tong, Bo Yang, Xianfu Wei, Di Qiua, Kui Lu, Org. Chem. Front., 2018, 5, 2636.
[11] Copper-catalyzed Direct Trifluoromethylthiolation of Indoles by tert-Butyl 2-((trifluoromethyl)sulfonyl)hydrazine-1-carboxylate. Kui Lu,* Quan Li, Xiaolan Xi, Yuna Huang, Zhi Gong, Peng Yu, Xia Zhao*, Org. Chem. Front., 2018, 5, 3088.
[12] Visible-Light-Driven Synthesis of Arylstannanes from Arylazo Sulfones. Chang Lian, Guanglu Yue, Jinshan Mao, Danyang Liu, Yi Ding, Zerong Liu, Di Qiu,* Xia Zhao,* Kui Lu, Maurizio Fagnoni, Stefano Protti*, Org. Lett., 2019, 21, 5187.
[13] Synthesis of a-Trifluoromethyl Ethanone Oximes via the Three-component Reaction of Aryl-substituted Ethylenes, tert-Butyl Nitrite, and the Langlois Reagent. Kui Lu,* Xianfu Wei, Quan Li, Yuxuan Li, Liangshuo Ji, Erbing Hua,* Yujie Dai, Xia Zhao*, Org. Chem. Front., 2019, 6, 3766.
(14) Metal-Free sp3 CSCF3 Coupling Reactions Between Cycloketone Oxime Esters and Strifluoromethyl 4Methylbenzenesulfonothioate. Xia Zhao,* Miaomiao Tian, Liangshuo Ji, Junjie Liu, Kui Lu, Org. Lett., 2020, 22, 863.
(15) Metal-Free Difluoromethylselenolation of Arylamines Under Visible-light Photocatalysis. Kui Lu,* Quan Li, Xiaolan Xi, Ting Zhou, Xia Zhao*, J. Org. Chem., 2020, 85, 1224.
(16) Metal-Free Trifluoromethylthiolation of Arylazo Sulfones. Ankun Li, Yuxuan Li, Junjie Liu, Jingqi Chen, Kui Lu, Di Qiu, Maurizio Fagnoni, Stefano Protti,* Xia Zhao *, J. Org. Chem. 2021, 86, 1292.
(17) Visible-Light-Promoted Selenocyanation of Cyclobutanone Oxime Esters Using Potassium Selenocyanate. Xia Zhao,* Liangshuo Ji, Yu Gao, Tengteng Sun, Jiamin Qiao, Ankun Li, and Kui Lu., J. Org. Chem., 2021, 86, 11399.