陈晨 副教授 E-mail:tjnuchenchen@163.com
男,博士研究生、博士学位、硕士生导师
入选2019年天津市高校青年后备人才支持计划
入选2017天津市“131”创新型人才培养工程第三层次人选
研究方向:金属导向的有机合成方法学、绿色化学
主要研究经历:
2010.09 - 2015.06 华东理工大学 博士研究生
2015.06 - 2015.10 康龙化成(北京)新药技术股份有限公司 高级有机合成研究员
2015.10 - 2016.10 安特卫普大学(比利时) 博士后研究员
2016.11 - 2017.03 博诺康源(北京)药业科技有限公司 高级有机合成研究员
2017.03 – 今 威尼斯wns885566 威尼斯wns885566有机化学教研室 教学科研
主持科研项目:
国家自然科学基金:基于含氟C,C-钯环中间体合成含氟杂环化合物的反应研究(21901184)
天津市自然科学基金:基于二氧化碳化学和有机膦化学的合成转化(20JCQNJC00400)
天津市高等学校科技发展基金计划项目基金:钯催化含氟异噁唑啉衍生物的合成方法研究(2018KJ159)
威尼斯wns885566博士基金:利用Catellani反应实现 6-三氟甲基菲啶化合物的合成(043135202-XB1703)
威尼斯wns885566省部级重点实验室开放研究基金:过渡金属催化下乙腈作为氰源的氰化反应研究
讲授课程:
有机化学;有机化学实验;有机化合物结构分析
代表性论文:
1. Chen Chen,* Yuebo Wang, Xiaonan Shi, Wan Sun, Jinghui Zhao, Yan-Ping Zhu, Liying Liu and Bolin Zhu*, Palladium-Catalyzed C‑2 and C‑3 Dual C-H Functionalization of Indoles: Synthesis of Fluorinated Isocryptolepine Analogues. Org. Lett., 2020, 22, 4097-4102.
2. Chen Chen*, Yinwei Bao, Jinghui Zhao and Bolin Zhu*, Silver-Promoted Cascade Radical Cyclization of γ, δ-Unsaturated Oxime Esters with P(O)H Compounds: Synthesis of Phosphorylated Pyrrolines. Chem. Commun., 2019, 55, 14697-14700.
3. Zhuo Wang, Tongyu Li, Jinghui Zhao, Xiaonan Shi, Dequan Jiao, Han Zheng, Chen Chen* and Bolin Zhu*, Expeditious Synthesis of 6-Fluoroalkyl-Phenanthridines via Palladium-Catalyzed Norbornene-Mediated Dehydrogenative Annulation. Org. Lett., 2018, 20, 6640-6645.
4. Chen Chen*, Jinghui Zhao, Xiaonan Shi, Liying Liu, Yan-Ping Zhu, Wan Sun and Bolin Zhu*, Recent Advances in Cyclization Reactions of Unsaturated Oxime Esters (Ethers): Synthesis of Versatile Functionalized Nitrogen-Containing Scaffolds, Org. Chem. Front., 2020, 7, 1948-1969.
5. Chen Chen*, Liying Liu, Wan Sun, Jie Ding, Yan-Ping Zhu and Bolin Zhu*, Pd/NBE-Catalyzed Sequential Carbamoylation/Olefination of Aryl Iodides, Org. Chem. Front., 2020, 7, 3179-3185.
6. Chen Chen*, Wan Sun, Liying Liu, Jinghui Zhao, Yujie Huang, Xiaonan Shi, Jie Ding, Dequan Jiao and Bolin Zhu*, Palladium-Catalyzed Domino Heck-Disilylation and Heck-Monosilylation of Alkene-Tethered Carbamoyl Chlorides: Synthesis of Versatile Silylated Oxindoles, Org. Chem. Front., 2021, 8, 2250-2255.
7. Chen Chen*, Jie Ding, Liying Liu, Yujie Huang and Bolin Zhu*, Palladium-Catalyzed Domino Cyclization/Phosphorylation of gem-Dibromoolefins with P(O)H Compounds: Synthesis of Phosphorylated Heteroaromatics, Adv. Synth. Catal., 2022, 364, 200-205.
8. Chen Chen*, Yujie Huang, Jie Ding, Liying Liu and Bolin Zhu*, Palladium-Catalyzed Carbamoyl-Carbamoylation/ Carboxylation/Thioesterification of Alkene-Tethered Carbamoyl Chlorides Using Mo(CO)6 as the Carbonyl Source, Adv. Synth. Catal., 2022, 364, 794-801.
9. Yuebo Wang, Jie Ding, Jinghui Zhao, Wan Sun, Chang Lian, Chen Chen* and Bolin Zhu*, Iminyl Radical-Promoted Imino Sulfonylation, Imino Cyanogenation and Imino Thiocyanation of γ,δ-Unsaturated Oxime Esters: Synthesis of Versatile Functionalized Pyrrolines, Org. Chem. Front., 2019, 6, 2240-2244.
10. Fang Yang, Wan Sun, Haifang Meng, Mengjia Chen, Chen Chen* and Bolin Zhu*, Palladium-Catalyzed Synthesis of Spirooxindoles and [3,4]-Fused Oxindoles from Alkene-Tethered Carbamoyl Chlorides, Org. Chem. Front., 2021, 8, 283-287.