邢思洋，男，1985年8月生，2007年毕业于南开大学威尼斯wns885566，获理学学士学位，2012年6月毕业于南开大学元素有机化学研究所，获理学博士学位，2012年7月进入威尼斯wns885566工作。

主要研究方向：有机合成化学与应用有机化学。

以生物活性天然产物、医药分子等为目标导向，主要发展适应于绿色化学和可持续发展化学的有机合成新方法。近年来我们合成了若干含有氮丙啶、环氧、三唑等的多官能团化合物，通过对催化体系、反应试剂等的选择，对这些多官能团化合物的串联环化反应进行精准调控，经由各自不同的反应路径，给出多种结构新颖的杂环化合物。

主持项目：

1. 聚酰亚胺单体的制备，横向项目，22万，2022.4-2023.4

2. 三种取代苯乙烯聚合物的合成研究，横向项目，10.5万，2021.4-2022.4

3. 二芳基取代环丙烷衍生物的合成，横向项目，4.3万，2018.4-2019.4

4. 氮丙啶串联环化反应在合成螺环化合物中的应用, 天津市自然科学基金青年基金, 6万，2018.4-2021.3

5. 3-烯基吲哚的串联环化反应研究, 威尼斯wns885566省部级重点实验室开放研究基金, 1.5万, 2018.1-2018.12。

6. 氮杂环丙烷开环和迈克尔加成参与的选择性串联环化反应,威尼斯wns885566省部级重点实验室开放研究基金, 1.5万, 2017.1-2017.12。

7. 天津市“131”创新型人才培养工程第三层次支持计划，2万，2016.1-2017.1

8. 路易斯酸催化下双酯基苯并环丁烷的环加成反应研究, 国家自然科学基金青年基金, 25万, 2014.1-2016.12

9. 通过串联反应构筑苯并呋喃骨架及其在合成中的应用, 威尼斯wns885566引进人才基金, 4万，2013.1-2016.1

指导学生获奖情况：

1.指导研究生获得研究生国家奖学金2项

2. 指导研究生获得校级优秀毕业论文3篇

3. 指导本科生获校级优秀毕业论文1篇

4. 指导大创项目国家级1项

5. 指导大创项目校级2项

发表文章：

1. Diastereoselective Access to cis-1,4-Disubstitued Tetrahydro-γ-carbolines via a [Cp*RhCl2]2-Catalyzed Formal [3+3] Cycloaddition, Siyang Xing*, Tingxuan Gao, Changkun Jin, Hongguo Dong, Xueying Shao, Kui Wang* and Bolin Zhu*, Adv. Synth. Catal. 2023, 365, 104–109 .

2. Construction of Bridged Aza- and Oxa-[n.2.1] Skeletons via an Intramolecular Formal [3+2] Cycloaddition of Aziridines and Epoxides with Electron-deficient Alkenes, Siyang Xing,* Yuhan Wang, Changkun Jin, Shaochen Shi, Yihui Zhang, Ziya Liao, Kui Wang* and Bolin Zhu*, J. Org. Chem. 2022, 87, 6426-6431

3. Construction of 4-spiroannulated tetrahydroisoquinoline skeletons via a sequential ring opening of aziridines and Pictet-Spengler reaction, Siyang Xing*, Chenyu Wang, Tingxuan Gao, Yuhan Wang, Hongzheng Wang, Hanfei Wang, Kui Wang*, Bolin Zhu *, New J. Chem. 2022, 46, 2553-2558

4. A Stepwise Synthesis of Spiroindoline Compounds via Ring Opening of Aziridines and C-H Activation/Cyclization, Siyang Xing*, Hanyu Xia, Chenyu Wang, Yuhan Wang, Lu Hao, Kui Wang* and Bolin Zhu*, Adv. Synth. Catal. 2021, 363, 1044-1049

5. General and Efficient Synthesis of 1,2-Dihydropyrrolo[3,4-b]indol-3-ones via a Formal [3+2] Cycloaddition Initiated by C-H Activation, Siyang Xing*, Junsuo Guo, Yuhan Wang, Chenyu Wang, Kui Wang*, Bolin Zhu*, Organic Chemistry Frontiers, 2020, 7, 4057-4063

6. Rapid and Efficient Construction of Indolizino[3,4,5‐ab]isoindole Skeletons by a Rhodium‐Catalyzed Tandem Reaction, Chang Liu, Shaonan Wu, Wan Sun, Haifang Meng, Siyang Xing*, Bolin Zhu*, Asian. J. Org. Chem. 2020, 9, 68-72 

7. Access to 1,2,3-Triazole-Fused Isoindolines via an Unexpected Lewis Acid Catalyzed Anulation, Xin Wang, Mengpei Bai, Meiqi Pei, Xinrui Xu, Die Wu, Siyang Xing*, Kui Wang*, Bolin Zhu* and Hanyu Xia, Tetrahedron Letters, 2019, 60, 151151

8. Diastereoselective Access to 2‐Aminoindanones via the Rhodium(II)‐Catalyzed Tandem Reaction Involving O‐H Insertion and Michael Addition, Siyang Xing*, Hanyu Xia, Xin Wang, Die Wu, Xinrui Xu, Yunran Su, Kui Wang*, Bolin Zhu* and Junshuo Guo, Org. Chem. Front. 2019, 6, 3121–3126

9. Diastereoselective Construction of 2-Aminoindanones via an In(OTf)3-Catalyzed Domino Reaction, Siyang Xing*, Hanyu Xia, Junshuo Guo, Chenchen Zou, Tingxuan Gao, Kui Wang*, Bolin Zhu*, Meiqi Pei and Mengpei Bai, J. Org. Chem. 2019, 84, 8984-8997

10. Highly Efficient Construction of Pentacyclic Carboline-Containing Salts via a [Cp*RhCl2](2)-Catalyzed Tandem Reaction, Zhuo Wang, Tongyu Li, Siyang Xing*, Bolin Zhu*,  Asian. J. Org. Chem. 2019, 8, 191-195  

11. Substitution-Controlled Selective Formation of Hexahydrobenz[e]isoindoles and 3-Benzazepines via In(OTf)3-Catalyzed Tandem Annulations, Siyang Xing*, Nan Gu, Xin Wang, Jingyi Liu, Chunyan Xing, Kui Wang*, Bolin Zhu*, Org. Lett. 2018, 20, 5680-5683

12. Reactivity of Alkyne Insertion and Catalytic Activity of Five- and Six-Membered Cyclometalated Phosphine Complexes of Iridium, Tongyu Li, Zhuo Wang, Kai Liu, Siyang Xing, Bolin Zhu*, Eur. J. Inorg. Chem. 2018, 3195-3202.  

13. Facile and Practical Synthesis of beta-carbolinium Salts and gamma-Carbolinium Salts via Rhodium-Catalyzed Three-component Reactions, Zhuo Wang, Tongyu Li, Siyang Xing*, Bolin Zhu*, Org. Biomol. Chem. 2018, 16, 5021-5026  

14. Diastereoselective Synthesis of cis-1,3-Disubstituted Isoindolines via a Highly Site-selective Tandem Cyclization Reaction, Siyang Xing*, Hong Cui, Jiajing Qin, Nan Gu, Bowei Zhang, Kui Wang*, Ying Wang*, Li Xia, Yumeng Wang, Org. Chem. Front. 2018, 5, 1950-1956

15. Synthesis of (−)-Pyrido[3,4-b]homotropane (PHT) and (±)-PHT via an Intramolecular Cross [3+2] Cycloaddition Strategy, Bingxia Sun, Jun Ren, Siyang Xing*, Zhongwen Wang*, Adv. Synth. Catal. 2018, 360, 1529-1537

16. Construction of 4‐Isochromanones through Cu(OTf)2‐Catalysed Sequential C=O and C–O Bond Formation, Siyang Xing*, Nan Gu, Jiajing Qin, Hong Cui, Yan Li, Kui Wang*, Dawei Tian*, Bo Chen, Guo Yu, Eur. J. Org. Chem. 2018, 926-931

17. AgOTf-catalyzed Sequential Synthesis of 4-Isoquinolones via Oxidative Ring Opening of Aziridines and aza-Michael addition, Siyang Xing*, Hong Cui, Nan Gu, Ying Li, Kui Wang*, Dawei Tian*, Jiajing Qin, Qiaoyang Liu, Org. Biomol. Chem. 2017, 15, 8308-8312

18. Facile, Efficient and Diastereoselective Construction of Indane-Fused Pyrrolidin-2-ones via a Potassium Hydroxide-Catalyzed Domino Reaction, Siyang Xing*, Jing Ren, Kui Wang*, Hong Cui, Tian Xia, Ming Zhang, Dandan Wang, Adv. Synth. Catal. 2016, 358, 3093-3099

19. Diastereoselective Synthesis of Substituted Tetrahydroisoquinolines and Isoindolines via a Silver(I) Triflate‐Promoted Tandem Reaction, Siyang Xing*, Jing Ren, Kui Wang*, Hong Cui, Han Yan, Wenrui Li, Adv. Synth. Catal. 2016, 358, 532-538

20. Lewis Acid Promoted Three-component Reactions of Aziridines, Arenes and Aldehydes: an Efficient and Diastereoselective Synthesis of cis-1,4-Disubstituted Tetrahydroisoquinolines, Siyang Xing*, Jing Ren, Kui Wang*, Hong Cui, Wenrui Li, Han Yan, Tetrahedron 2015, 71, 6290-6299

21. Lewis Acid Catalyzed Intramolecular [3+2] Cross Cycloadditions of Cobalt-Alkynylcyclopropane 1,1-Diesters with Carbonyls for Construction of Medium-Sized and Polycyclic Skeletons”, Junhui Zhang, Siyang Xing, Jun Ren, Shende Jiang*, and Zhongwen Wang* Org. Lett., 2015, 17 , 218.

22. Lewis Acid Catalyzed Intramolecular  [3+2] Cross-Cycloaddition of Donor-Acceptor Cyclopropanes with Carbonyls: A General Strategy for the Construction of Acetal[n.2.1] Skeletons， Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren, Zhongwen Wang*, Angew. Chem. Int. Ed. 2011, 50, 12605.

23. Efficient Construction of Oxa- and Aza-[n.2.1] Skeletons: Lewis Acid Catalyzed Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diesters with Carbonyls and Imines, Siyang Xing, Wenyan Pan, Chang Liu, Jun Ren, Zhongwen Wang*, Angew. Chem. Int. Ed. 2010, 49, 3215.

24. Total Synthesis of (±)-Bruguierol A via an Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diester, Bao Hu, Siyang Xing, Jun Ren, Zhongwen Wang*, Tetrahedron 2010, 66, 5671.

25. A Highly Site-, Regio-, and Stereoselective Lewis Acid Catalyzed Formal [3+3] Cycloaddition of Methylenecyclopropane-1,1-Diesters with C,N-Diarylnitrones, Bao Hu, Jianlin Zhu, Siyang Xing, Jie Fang, Ding Du, Zhongwen Wang*, Chem. Eur. J. 2009, 15, 324.

26. Lewis Acid Catalyzed Ring-Opening Intramolecular Friedel−Crafts Alkylation of Methylenecyclopropane 1,1-Diesters, Bao Hu, Siyang Xing, Zhongwen Wang*, Org. Lett. 2008, 10, 5481.