姓名：钱璟    

出生日期：1972年1月  

实验室：明理楼B区528  

职称：教授、硕士生导师  

学历：博士  

Email：qianjinger@aliyun.com; hxxyqj@mail.tjnu.edu.cn  

[个人简历]      

钱璟，女，博士，教授。1972年1月出生，1990年～1994年在河北师范大学化学系学习，获理学学士学位；1994年～2001年在河北保定学院化学系任教；2001年～2004年在河北大学化学与环境工程学院学习，获理学硕士学位；2004年～2007年在南开大学威尼斯wns885566学习，获理学博士学位；2007年入职威尼斯wns885566从事教学科研工作。

[讲授课程] 

主讲本科生《无机化学》、《无机化学实验》基础课；开设《生物无机化学》、《药物化学》、《药物分子设计》等专业选修课。

 [研究领域]    

◆ 纳米靶向抗肿瘤药物

◆ 上转换荧光探针  

◆ 金属功能酶  

 [科研项目]      

1. 国家自然科学基金-面上项目（2016.01-2019.12），“靶向定点水解核酸的配合物合成、作用机制及其结构和功能的相关性”，主持；  

2. 天津市应用基础与前沿技术研究计划-面上项目（2015.04-2018.03），“新型核酸定点水解催化剂的合成、性质及机理研究”，主持；  

3. 天津市高等学校科技发展基金计划项目(2007-2010)，“配合物与DNA的分子识别及反应机理研究”，主持；  

4. 威尼斯wns885566博士基金项目(2008-2010)，“基于协同效应的双核配合物催化核酸裂解的分子设计”主持；  

[十篇代表性论文]      

(1). Jin-Yang Liu,^a Na Liu,^b Yue Wu,^a Xiao-Min Ning,^a Wen-Chao Zhang,^b,* and Jing Qian^a,*. NaErF₄-Based Nanocarrier for Enhanced Ferroptosis Therapy of Cancer. ACS Appl. Nano Mater. 2023, 6, 270−282.

(2). Yue Wu,^a Na Liu,^b Yue Wu,^a Xiao-Xia Ren,^a Wen-Chao Zhang,^b,* and Jing Qian^a,*.  Nanocarriers Based on NaTmF₄:0.5%Er³⁺@NaLuF₄ Upconversion Nanoparticles with Enhanced Near-Infrared Luminescence for Combination Tumor Treatment. ACS Appl. Nano Mater. 2023, 6, 2171−2183.

(3). Xiaomin Ning,^a Na Liu,^b Jinyang Liu,^a Yue Wu^a Jing Qian^a*, Wenchao Zhang^b*, Wen Gu^c. "Temperature sensing and bioimaging realized in NaErF₄:40%Tm@NaYF₄ with extremely intense red upconversion and suitable R/G emission ratio" Optical Materials, 2022, 131,112659.

(4). Mei-Hua Lin, Xiao-Xia Ren, Xiao-Min Ning, Dong-Yang Liu, and Jing Qian*. " Improving Ion Selectivity of 1,4,7-Triazacyclononane-Based Receptor by Zinc Coordination: “Turn-On” Chemosensor for Br⁻ and Fe³⁺ Ions", Langmuir, 2020, 36, 13218−13226.

(5). Ming Liu,^a Xue-Qing Song,^b Yuan-Di Wu,^a Jing Qian*^a and Jing-Yuan Xu*^b. "Cu(II)-TACN complexes selectively induce antitumor activity in HepG-2 cells via DNA damage and mitochondrial-ROS-mediated apoptosis" Dalton Trans., 2020, 49, 114–123.

(6). Jing Qian*, Shasha Yu, Wenjun Wang, Liping Wang, Jinlei Tian* and Shiping Yan. "Efficient single-strand cleavage of DNA mediated by a MnIIIMnIV-based artificial nuclease". Dalton Transations., 2014, 43, 2646-2655.

(7). Jing Qian*, Liping Wang, Wen Gu, Xin Liu, Jinlei Tian*, Shiping Yan. “Efficient double-strand cleavage of DNA mediated by Zn(II)-based artificial nucleases”. Dalton Transations., 2011, 40, 5617–5624.

(8). Jing Qian, Xiaofang Ma, Jinlei Tian, Wen Gu, Jing Shang, Xin Liu, Shiping Yan*. “Hydrolytic cleavage of double-strand DNA by the water-soluble dicobalt(III) complexes of 1,4,7-Triazacyclononane-N-acetate”. Journal of Inorganic Biochemistry. 2010, 104, 993–999,.

(9). Jing Qian, Jinlei Tian, Wen Gu, Song Gao, Xin Liu, Shiping Yan*, Joan Ribas*, Daizheng Liao. “A New Fe₆ Ferric Cluster: Synthesis, Crystal Structure and Magnetic Properties”. Dalton Transations., 2008, 6948–6952.

(10). Jing Qian, Wen Gu, Hui Liu, Feng-xian Gao, Li Feng, Shi-ping Yan*, Dai-zheng Liao, and Peng Cheng. “The first dinuclear copper(II) and zinc(II) complexes containing novel Bis-TACN: syntheses, structures, and DNA cleavage activities”. Dalton Transations., 2007, 1060–1066.